Lub npe dav: | Cagrilintide |
Cas No.: | 1415456-99-3 |
Molecular Formula: | C194H312N54O59S2 |
Molecular Luj: | 4109 g / mol |
Qhov tsos: | Dawb hmoov |
Daim ntawv thov: | Cagrilintide yog ib hom tshuaj siv los kho mob ntshav qab zib hom 2. Nws yog ib qho hluavtaws peptide uas ua raws li agonist ntawm glucagon-zoo li peptide-1 (GLP-1) receptor. GLP-1 yog cov tshuaj hormones tsim tawm hauv plab uas pab tswj cov ntshav qab zib. Caglilin peptides ua los ntawm kev txhawb nqa GLP-1 receptor, ua rau muaj cov tshuaj insulin ntau ntxiv, txo qis glucagon secretion, thiab ua rau lub plab zom mov qeeb. Qhov no thaum kawg pab tswj cov ntshav qab zib hauv cov neeg mob ntshav qab zib hom 2.Ntxiv rau nws cov teebmeem ntawm insulin thiab glucagon secretion, caglilintide muaj lwm yam txiaj ntsig hauv kev kho mob ntshav qab zib hom 2. Nws tau raug pom los txhawb qhov kev xav ntawm kev puv, ua rau txo qis kev noj zaub mov thiab poob phaus hauv qee cov neeg mob. Qhov no yog qhov tseem ceeb vim tias kev poob phaus yog txuam nrog kev txhim kho glycemic tswj thiab txo kev pheej hmoo ntawm cov teeb meem plawv hauv cov neeg mob ntshav qab zib hom 2. Tsis tas li ntawd, canagrelin tide tau pom tias muaj cov txiaj ntsig ntawm cov hlab plawv. Nws tau pom tias yuav txhim kho lub plawv ua haujlwm thiab txo qhov mob ntawm cov hlab plawv, ib qho teeb meem tshwm sim hauv cov neeg mob ntshav qab zib. Qhov no ua rau nws muaj txiaj ntsig zoo rau cov neeg mob ntshav qab zib thiab kab mob plawv. Canagrelin feem ntau yog txhaj tshuaj subcutaneously ib zaug lossis ob zaug ib hnub. Nws yog ib qho tseem ceeb rau cov neeg mob kom tau txais kev kawm tsim nyog thiab kev taw qhia txog kev tswj hwm tus kheej li cas kom siv tau zoo thiab nyab xeeb. Raws li nrog rau txhua yam tshuaj, caglilintide muaj peev xwm tshwm sim. Cov kev mob tshwm sim feem ntau muaj xws li xeev siab, ntuav thiab raws plab. Cov kev mob tshwm sim no feem ntau txhim kho lub sijhawm thaum lub cev hloov kho rau cov tshuaj. Canagrelin kuj tseem tuaj yeem ua rau muaj kev pheej hmoo ntawm hypoglycemia, tshwj xeeb tshaj yog thaum siv nrog lwm cov tshuaj tiv thaiv kab mob. Kev saib xyuas cov ntshav qab zib kom tsis tu ncua yog tsim nyog los tiv thaiv thiab tswj ntshav qab zib. Zuag qhia tag nrho, caglilin tide yog qhov tseem ceeb ntxiv rau cov kev kho mob rau cov neeg mob ntshav qab zib hom 2. Nws pab tswj cov ntshav qab zib, txhawb kev poob phaus, thiab muaj cov txiaj ntsig ntawm cov hlab plawv. Txawm li cas los xij, nws yog ib qho tseem ceeb rau cov neeg mob ua hauj lwm nrog lawv tus kws kho mob kom txiav txim siab seb canagrelintide puas yog kev xaiv rau lawv thiab xyuas kom meej tias cov tshuaj siv tau zoo thiab muaj txiaj ntsig. |
Pob: | aluminium foil hnab los yog txhuas TIN lossis raws li tus neeg siv khoom xav tau |
1 | Cov kws tshaj lij rau peptide APIs los ntawm Tuam Tshoj. |
2 | 16 cov kab ntau lawm uas muaj peev xwm loj txaus nrog cov nqi sib tw |
3 | Cov khoom yog tsim nyob rau hauv US FDA thiab EDQM pom zoo site. |
A: Yog lawm, peb tuaj yeem ntim raws li koj xav tau.
A: LC pom thiab TT ua ntej lub sijhawm them nyiaj nyiam.
A: Yog, thov muab koj cov lus qhia zoo, peb yuav kuaj nrog peb R & D thiab sim ua kom haum koj cov lus qhia zoo.